daflon. For the Relief and Prevention of Hemorrhoid disease.
How does daflon work?
daflon is a convenient oral venoactive treatment that tackles the root problem of Hemorrhoids by directly acting on the veins which have become dilated and inflamed during a Hemorrhoidal episode, 1 effectively treating the disease by reducing its associated signs and symptoms.
For long-term management of Hemorrhoids, daflon strengthens the overall tone of your veins, helps to improve blood flow, as well as reduces venous congestion. 1
Formulated for Fast Absorption and Relief
daflon is a clinically proven, effective and discrete oral treatment derived from natural ingredients and specially formulated for maximum absorption. 1
This improved absorption means that daflon can rapidly reach the affected veins to efficiently reduce the duration, intensity and recurrence of Hemorrhoid episodes.
In addition, there are different dosing options for fast-acting treatment of acute episodes and ongoing maintenance for recurring Hemorrhoid Disease. 2
Rapid Relief
daflon is clinically proven to quickly and effectively treat Hemorrhoidal episodes for rapid relief. 1,2 In just two days, 42% of users demonstrated a reduction in their symptoms and in only three days, 80% reported that their bleeding had stopped. After a single week, most people reported that their symptoms, including bleeding, pain and discharge, had resolved.
daflon can also be used for up to two months to treat chronic and recurring Hemorrhoids. With just one tablet a day, 71% of users reported fewer instances of acute episodes. 5
Rapid relief for Acute Hemorrhoids
At 2 days
42% of patients experienced mild reduction of symptoms
At 3 days
80% of patients' bleeding stopped 2
At 7 days
94% of patients' bleeding stopped 2
84% of patients' pain stopped 4
81% of patients' discharge stopped 4
Ongoing treatment
for Recurrent Hemorrhoids
At 2 months
31% Less severe symptoms
43% Shorter duration of symptoms
71% Fewer recurrences
Why you should treat continuously
Although Hemorrhoid Disease can be treated, it is known to be a progressive inflammatory condition which can recur at anytime. In fact, 1 in 4 patients have shown to experience Hemorrhoids again within 7 months of a resolved episode. 7
daflon is a venoactive drug treatment recommended for the treatment of all grades of Hemorrhoid Disease. 1 By treating early and regularly with daflon, you can help prevent the recurrence of acute Hemorrhoid episodes and reduce the severity of symptoms. 5
Convenient Oral Dosing
The personal nature of Hemorrhoid symptoms may put you off from seeking treatment. daflon offers the convenience of a discreet over-the-counter oral treatment that quickly and effectively manages Hemorrhoid symptoms by treating the root cause, allowing you to become yourself again. 2
One week treatment for Acute Hemorrhoids
First 4 days:6 tabletsa day
Next 3 days:4 tabletsa day
Ongoing maintenance for Recurrent/Chronic Hemorrhoids
Up to 2 months1 tableta day
For use beyond 2 months, consult a healthcare professional
Naturally sourced, scientifically prepared.
The active ingredient in daflon is a micronise purified flavonoid fraction (MPFF) 6 containing 90% diosmin and 10% other flavonoids expressed as hesperidin.
daflon’s flavonoids are extracted from immature oranges that are rich in these naturally occurring plant chemicals. The compounds undergo a process of purification and refinement where the particles collide with each other at high speeds (micronisation), reducing them to tiny particles, less than 2 μm in size (micronise). These smaller particles are absorbed twice as easily by the body and are a key ingredient of daflon’s success as a treatment for improving vein health and tone in Chronic Venous Insufficiency and Hemorrhoids. 6
Safety Information:
daflon 500mg Safety Information
COMPOSITION*: Micronized purified flavonoid fraction 500mg: 450mg diosmin; 50mg flavonoids expressed as hesperidin. INDICATIONS*: Treatment of organic and functional chronic venous insufficiency of the lower limbs with the following symptoms: swollen legs; pain; nocturnal cramps. Treatment of chronic hemorrhoids and acute hemorrhoidal attacks. DOSAGE AND ADMINISTRATION*: In chronic conditions: 1000mg daily. In acute hemorrhoidal attacks: the dosage can be increased up to 3000mg daily. CONTRAINDICATIONS*: Hypersensitivity to the active substance or to any of the excipients. WARNINGS*: The administration of this product for the symptomatic treatment of acute haemorrhoids does not preclude treatment for other anal conditions. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free. INTERACTIONS*: None. FERTILITY*/ PREGNANCY*. BREASTFEEDING*: Avoid use of this product during pregnancy. Breast feeding is not recommended. DRIVE & USE MACHINES*. UNDESIRABLE EFFECTS*: Common: diarrhoea, dyspepsia, nausea, vomiting. Rare: dizziness, headache, malaise, rash, pruritis, urticaria. Uncommon: colitis. Frequency not known: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke’s oedema. OVERDOSE*. PROPERTIES*: Vascular protector and venotonic. Daflon 500mg acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. PRESENTATION*: Pack of 30 film-coated tablets of Daflon 500mg. SERVIER(S) PTE LTD 67 Ubi Avenue 1, #06-09 StarHub Green, Singapore 408942. www.servier.com
*For complete information, please refer to the Singapore Package Insert.
References:
- Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
- Misra MC, Parshad R. Randomized clinical trial of micronized flavonoids in the early control of bleeding due to acute internal hemorrhoids. Br J Surg. 2000;87:868-872.
- Garner RC, Garner JV, Gregory S, Whattam M, Calam A, Leong D. Comparison of the absorption of micronized (Daflon 500 mg) and nonmicronized 14C-diosmin tablets after oral administration to healthy volunteers by accelerator mass spectrometry and liquid scintillation counting. J Pharm Sci. 2002;91:32-40.
- Cospite M. Double-blind, placebo-controlled evaluation of clinical activity and safety of Daflon 500 mg in the treatment of acute hemorrhoids. Angiology. 1994;45:566-573.
- Godeberge P. Daflon 500mg is significantly more effective than placebo in the treatment of hemorrhoids. Phlebology. 1992;7(suppl 2):61-63.
- Summary of Product Characteristics Daflon 7. Greenspon. Thrombosed external hemorrhoids: outcome after conservative or surgical treatment J.Dis Colon Rectum 2004. 47(9):1493-8.
2024